Serpentine supravenous hyperpigmentation due to hydroxychloroquine

Serpentine supravenous hyperpigmentation

Serpentine supravenous hyperpigmentation is a peculiar cutaneous eruption that follows the path of vein after intravenous injection of the chemotherapeutic agent. The lesions gradually resolve spontaneously if administration of the offending agent is stopped through the affected limb. Drugs such as 5-fluorouracil, docetaxel, vinorelbine, hydroxychloroquine, fotemustine, and minocycline are impl...

Serpentine supravenous hyperpigmentation following cisplatin and pemetrexed chemotherapy.

E20 CUTIS WWW.CUTIS.COM To the Editor: Serpentine supravenous hyperpigmentation (SSH) is a rare phenomenon characterized by linear hyperpigmentation of the skin overlying veins secondary to intravenous antineoplastic therapy. The term was first suggested by Hrushesky1 in 1976 as an uncommon side effect of administering intravenous 5-fluorouracil (5-FU). Although 5-FU is the most frequent offend...

Chemotherapy-associated supravenous hyperpigmentation.

Hydroxychloroquine-Associated Hyperpigmentation Mimicking Elder Abuse

BACKGROUND Hydroxychloroquine may result in cutaneous dyschromia. Older individuals who are the victims of elder abuse can present with bruising and resolving ecchymoses. PURPOSE The features of hydroxychloroquine-associated hyperpigmentation are described, the mucosal and skin manifestations of elder abuse are reviewed, and the mucocutaneous mimickers of elder abuse are summarized. CASE RE...

Persistent serpentine supravenous hyperpigmented eruption in lepromatous leprosy after minocycline.

Persistent serpentine supravenous hyperpigmented eruption (PSSHE) is a peculiar patterned eruption characterised by hyperpigmented streaks following the superficial venous network on the skin. Unlike the superficial thrombophlebitis, it is characterised by underlying vessels that are patent. It has been described most commonly after injection of chemotherapeutic drugs. We describe a 40 year old...